Association of molecular variants of luteinizing hormone with male infertility
نویسندگان
چکیده
منابع مشابه
Association of molecular variants of luteinizing hormone with male infertility.
Luteinizing hormone (LH) stimulates the interstitial Leydig cells to produce testosterone, which is essential for spermatogenesis. Abnormalities in the function of LH may affect the process of spermatogenesis and thus result in infertility. The aim of this study was to determine the association of three known variants of LH (Gln54Arg [Trp8Arg; Ile15Thr] and Gly102Ser) with male infertility. A t...
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BACKGROUND High circulating luteinizing hormone (LH) level is a typical biochemical feature of polycystic ovary syndrome (PCOS) whose pathophysiology is still unclear. Certain mutations of LH and LH receptor (LHR) may lead to changes in bioactivity of these hormones. The aim of this study was determine the role of the LH and LHR polymorphisms in the pathogenesis of PCOS using a genetic approach...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2000
ISSN: 1460-2350
DOI: 10.1093/humrep/15.4.925